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Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
Published on: March 27, 2018
Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds
Sang-Soo Kim1, Heung Jae Park, Joungho Han
1Department of Chemical Engineering, Hanyang University, Seoul, Korea.
Biotechnology Letters
|October 24, 2003
Abstract:
Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.
