Coronary artery disease incidence between type II diabetic and non-diabetic patients with Leriche syndrome

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Murat Ozeren1, Mehmet Kaya, Mustafa Kar

  • 1Cardiovascular Surgery Department, Social Security Organization, Ankara Education and Research Hospital, Turkey. mozeren@yahoo.com

Indian Journal of Medical Sciences
|October 24, 2003
PubMed

Insights

Diabetic patients with Leriche syndrome often have advanced coronary artery disease (CAD). Coronary angiography and revascularization are recommended for select patients undergoing major vascular surgery.

Area of Science:

  • Cardiovascular Surgery
  • Vascular Surgery
  • Diabetology

Background:

  • Coronary artery disease (CAD) significantly impacts morbidity and mortality in patients undergoing major vascular surgery.
  • Management of CAD in this high-risk population remains a clinical challenge.

Purpose of the Study:

  • To investigate the incidence and severity of CAD in diabetic versus non-diabetic patients with Leriche syndrome.
  • To compare coronary angiographic findings and revascularization rates between these groups.

Main Methods:

  • 107 patients with Leriche syndrome were categorized based on diabetic status.
  • Coronary angiography was performed on all patients, with lesions evaluated for stenosis percentage.
  • Preoperative interventions like coronary bypass or percutaneous coronary intervention were considered for severe CAD.

Main Results:

  • Diabetic patients showed a higher prevalence of advanced or severe CAD (59%) compared to non-diabetics (38%).
  • Revascularization rates were similar between groups (37.8% diabetic vs. 45.7% non-diabetic).
  • Preoperative mortality rates were comparable (2.7% diabetic vs. 4.2% non-diabetic).

Conclusions:

  • Diabetes mellitus is associated with a higher likelihood of advanced coronary disease in patients with Leriche syndrome.
  • Coronary angiography and revascularization decisions should be individualized for patients requiring major vascular surgery.
Abstract

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