[Is the directed biopsy accurate?]

The aim of the present study was to evaluate the diagnostic accuracy of the colposcopically directed biopsy of cytologically signalized women. Retrospectively were analyzed sixty women aged between 20 and 69 (mean 37.4), to whom was performed colposcopically directed biopsy and consequent in the interval of no more than 3 months extended excision (to 30 of them--surgical conisation and to another 30--LLETZ/LEEP). Summarized data shows, that in 47 (78.3%) of them there are coincidence to one degree difference in the histological findings, and of the remain 13 cases--in 4 (6.7%) there are false positive results, and in 9 (15.0%)--false negative. The value of the sensitivity is 83% and of the predictive value of the positive results is 91.7%, which put them in the borders of the good performance of the diagnostic test. The conclusion is that the accuracy of the directed biopsy is determined by the presence or absence of the good correlation between cytological, colposcopical and histological investigation, as the implementation of the excisional biopsies enlarged the possibilities of the diagnostic protocol for the following adequate therapeutic action.