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Case studies in severe psoriasis: A clinical strategy.
Mark Lebwohl1, Alan Menter, John Koo
1Department of Dermatology, Mount Sinai School of Medicine, 1 Gustave Levy Place, Box 1047, New York, NY 10029-6574, USA.
The Journal of Dermatological Treatment
|October 28, 2003
Summary
Psoriasis significantly impacts quality of life, with many patients feeling undertreated. Toxicity-sparing strategies and treatment algorithms can optimize care for moderate-to-severe psoriasis.
Area of Science:
- Dermatology
- Quality of Life Research
Background:
- Psoriasis significantly affects patients' emotional, social, and physical well-being.
- Individuals with psoriasis report the lowest health-related quality of life among various chronic diseases.
Observation:
- A significant percentage of psoriasis patients feel their current treatment is insufficient.
- Existing treatments for psoriasis, while effective, carry potential long-term risks.
Findings:
- Toxicity-sparing strategies, including combination, rotational, and sequential regimens, can manage moderate-to-severe psoriasis while minimizing risk.
- Treatment algorithms guide the optimal use of phototherapy, cytotoxic agents, retinoids, and biologics for specific patient needs.
Implications:
- Developing and implementing structured treatment algorithms is crucial for effective psoriasis management.
- Optimizing treatment strategies can improve the quality of life for individuals with moderate-to-severe psoriasis.