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Peripheral giant cell granuloma associated with dental implants
Abraham Hirshberg1, Avital Kozlovsky, Devorah Schwartz-Arad
1Department of Oral Pathology and Oral Medicine, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv, Israel. hirshmd@post.tau.ac.il
Journal of Periodontology
|October 31, 2003
Summary
Peripheral giant cell granuloma (PGCG) can occur around dental implants. Early detection and surgical removal are crucial to prevent implant failure due to PGCG
Area of Science:
- Oral pathology
- Dental implantology
- Reactive hyperplastic lesions
Background:
- Peripheral giant cell granuloma (PGCG) is a reactive lesion typically found on gingival and alveolar mucosa.
- It is often associated with local irritation or trauma.
- The occurrence of PGCG in peri-implant settings is less understood.
Purpose of the Study:
- To evaluate the incidence of PGCG in peri-implant lesions.
- To determine the correlation between PGCG and dental implant failure.
- To discuss the pathogenesis of PGCG in relation to dental implants.
Main Methods:
- Analysis of 25 peri-implant biopsy specimens histologically examined between 1999 and 2001.
- Tissue sections were stained with hematoxylin and eosin for microscopic evaluation.
Main Results:
- Three cases (12%) of PGCG were identified in the peri-implant specimens.
- Lesions occurred in the mandible and maxilla, presenting as exophytic, bleeding masses.
- All cases showed recurrence after curettage; two implants were removed due to bone loss or recurrence.
Conclusions:
- Peripheral giant cell granuloma can develop around dental implants, mimicking classical PGCG clinically.
- The aggressive nature and high recurrence rate of PGCG pose a risk to dental implant survival.
- Prompt diagnosis and surgical intervention are essential for successful management and to prevent implant loss.