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Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection
Thomas D Wang1, Christopher H Contag, Michael J Mandella
1Stanford University School of Medicine, Stanford, California 94305, USA. tdwang@stanford.edu
Optics Letters
|November 1, 2003
Abstract:
We present a dual-axes confocal microscope that employs postobjective scanning and low-coherence heterodyne detection to collect vertical cross-sectional images from biological tissue with high axial resolution, reduced noise from scattered light, deep tissue penetration, and a large dynamic range. This architecture can be scaled down to millimeter dimensions with microelectromechanical systems technology for performance of in vivo optical biopsy.