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A case of Raynaud's disease with uterine cancer producing interleukin-6
A Murashima1, Y Takasaki, H Hashimoto
1Department of Internal Medicine, Juntendo University, School of Medicine, Tokyo, Japan.
Abstract:
A case of cervical cancer of the uterine producing interleukin-6(IL-6) in a patient who suffered from Raynaud's phenomenon is described. Her serum contained anti SS-A antibody. The cancer was removed surgically. High level of IL-6 activity was detected in the culture supernatant of the resected cancer cells. After operation, Raynaud's phenomenon had improved and anti SS-A antibody had disappeared. This case shows us that IL-6 produced by malignant tumour might induce autoimmune connective tissue disease-like symptoms.

