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Related Experiment Videos

Endometrial dating in the conception cycle.

K Andoh1, H Mizunuma, Y Nakazato

  • 1Department of Obstetrics and Gynecology, Gunma University, School of Medicine, Japan.

Fertility and Sterility
|December 1, 1992
PubMed
Summary
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Endometrial dating in conception cycles is in-phase until day 12 post-luteinizing hormone (LH) surge. After day 12, apparent out-of-phase findings in endometrial biopsies may indicate early pregnancy.

Area of Science:

  • Reproductive Endocrinology
  • Gynecology

Background:

  • Accurate endometrial dating is crucial for assessing reproductive success.
  • The luteal phase, particularly after the luteinizing hormone (LH) surge, is a critical window for implantation.

Purpose of the Study:

  • To investigate the accuracy of endometrial dating during the conception cycle.
  • To correlate endometrial biopsy findings with conception and progesterone levels.

Main Methods:

  • Endometrial biopsies were collected during the luteal phase of 185 women undergoing fertility treatment.
  • Biopsies were dated based on urinary LH surge, and correlated with serum progesterone levels.

Main Results:

  • Women who conceived had in-phase endometrial biopsies 7-11 days after the LH surge.

Related Experiment Videos

  • On day 12 post-LH surge, 4 out of 5 women who conceived showed delayed stromal development, suggesting a link to conception.

    • Conclusions:

    • Endometrial dating is reliable until day 12 of the luteal phase in conception cycles.
    • Apparent out-of-phase endometrial development on day 12 may be an early indicator of gestational hyperplasia.