Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mortality after osteoporotic fractures.

O Johnell1, J A Kanis, A Odén

  • 1Department of Orthopaedics, Malmö University Hospital, Malmö, Sweden.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|November 1, 2003
PubMed
Summary

Mortality risk increases significantly after osteoporotic fractures of the spine, shoulder, and hip, especially immediately following the event. This risk decreases over time, but remains elevated compared to the general population.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristics of recurrent fractures.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2017
Same author

Imminent risk of fracture after fracture.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

Increased risk of hip fracture among spouses-evidence of a homogamy effect.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

The T -786C, G894T, and Intron 4 VNTR (4a/b) Polymorphisms of the Endothelial Nitric Oxide Synthase Gene in Prostate Cancer Cases.

Genetika·2016

Area of Science:

  • Orthopedics
  • Gerontology
  • Epidemiology

Background:

  • Osteoporotic fractures are a significant health concern, particularly in aging populations.
  • Previous studies have indicated increased mortality following certain fractures, but patterns across multiple sites require further investigation.
  • Understanding mortality risks associated with osteoporotic fractures is crucial for public health strategies.

Purpose of the Study:

  • To investigate the temporal patterns of mortality after osteoporotic fractures at the spine, shoulder, hip, and forearm.
  • To compare mortality rates in fracture patients with the general population.
  • To identify risk factors and trends in mortality following these specific fracture types.

Main Methods:

  • Retrospective cohort study of 2,847 patients with osteoporotic fractures in Malmö, Sweden.

Related Experiment Videos

  • Utilized Poisson regression to analyze mortality rates immediately post-fracture and over time.
  • Compared fracture patient mortality data with sex-specific general population risks.

    • Main Results:

    • Mortality was significantly higher in patients with spine, shoulder, and hip fractures compared to the general population, except for forearm fractures.
    • Mortality risk was higher in men than women, but this difference diminished when adjusted for population risks.
    • Mortality risk decreased after the first year for spine, shoulder, and hip fractures, most notably for spine fractures.

    Conclusions:

    • Osteoporotic fractures, particularly at the spine, shoulder, and hip, are associated with increased mortality, with the highest risk occurring acutely post-fracture.
    • The observed decline in mortality risk over time suggests a potential reduction in fracture-related deaths.
    • The impact of early osteoporosis intervention on mitigating this excess mortality remains an area for future research.