Related Experiment Videos
Gadolinium-binding helix-turn-helix peptides: DNA-dependent MRI contrast agents
Peter Caravan1, Jaclyn M Greenwood, Joel T Welch
1EPIX Medical, Inc., 71 Rogers Street, Cambridge, MA 02142, USA.
Chemical Communications (Cambridge, England)
|November 5, 2003
Abstract:
A de novo designed gadolinium metallopeptide was found to be a very efficient relaxation agent, with 100% increase in relaxivity upon binding to DNA.
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