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Published on: January 26, 2019
Hospitalization for respiratory syncytial virus in the paediatric population in Spain
1Servicio de Microbiología, Hospital Donostia, Paseo Dr. Beguiristain s/n 20014 San Sebastián, Spain.
Insights
Community-acquired respiratory syncytial virus (RSV) infection frequently hospitalizes young children in Spain. Infants under one year old are most affected, highlighting the need for RSV prevention strategies.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Community-acquired respiratory syncytial virus (RSV) is a significant pathogen in pediatric populations.
- Understanding the incidence of RSV-related hospitalizations is crucial for public health planning.
Purpose of the Study:
- To determine the incidence of hospitalization for laboratory-confirmed RSV infection in children under five years old in southern Europe.
- To identify risk factors and demographic trends associated with RSV hospitalizations.
Main Methods:
- Population-based retrospective study analyzing data from July 1996 to June 2000.
- Inclusion of 15,700 children under five years old served by a single hospital.
- Laboratory confirmation of RSV in nasopharyngeal aspirates from children with acute respiratory infections.
Main Results:
- 390 RSV hospitalizations were detected; 83.3% of affected children were under one year old.
- Annual hospitalization rates were 37/1000 for infants under 6 months and 25/1000 for those under 1 year.
- 2.5% of infants under one year and 5% under three months were hospitalized; 7% required ICU admission, mostly neonates.
Conclusions:
- RSV infection is a frequent cause of hospitalization in young Spanish children, particularly those under one year.
- The high incidence underscores the need for effective RSV prevention strategies, including vaccines.
- RSV prevention should be a public health priority to reduce pediatric hospitalizations.
Abstract:
The aim of this population-based retrospective study was to determine the incidence of hospitalization for community-acquired, laboratory-confirmed respiratory syncytial virus (RSV) infection in an unselected paediatric population from southern Europe. The study was performed in an area with 15,700 children aged less than 5 years attended by a single hospital. The presence of RSV in nasopharyngeal aspirates from children with acute respiratory infection treated in the hospital was investigated in four seasons (July 1996-June 2000). A total of 390 episodes of hospitalization for RSV infection were detected and 83.3% of the children were aged less than 1 year old. The annual hospitalization rate was 37/1000 for infants aged less than 6 months and 25/1000 for those aged less than 1 year. During the study period, 2.5% of the infants younger than 1 year and approximately 5% of those younger than 3 months were hospitalized for RSV infection. The mean length of hospital stay was 5.9 days. Seven per cent of the patients required admission to the intensive care unit and more than half of these children were aged less than 1 month. In Spain, community-acquired RSV infection is a highly frequent cause of hospitalization in young children, especially in those aged less than 1 year. Prevention of RSV infection, through the development of vaccines and/or other strategies, should be a public health priority.
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