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Wernicke's encephalopathy in AIDS: a preventable cause of fatal neurological deficit
M L Alcaide1, D Jayaweera, L Espinoza
1Special Immunology, Division of Infectious Diseases, University of Miami, Infectious Diseases Clinical Research Unit, 1500 NW 12th Ave 8th Fl, West Miami, Florida 33136, USA. malcaide@hotmail.com
Abstract:
Wernicke's encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor nutritional status. We report a case of acute Wernicke's encephalopathy in a patient with AIDS without any predisposing risk factors for thiamine deficiency. In developing countries, without vitamin supplementation, this disorder may play a role in the morbidity and mortality associated with AIDS. We believe that thiamine supplementation should be considered in cachetic AIDS patients, especially where access to antiretroviral therapy is limited.
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