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Non-alcoholic fatty liver disease: the problems we are facing
1Department of Gastroenterology, People's Hospital, Beijing University, Beijing 100044, China. jingtongw@yahoo.com.cn
Objective:
To review the current state of research in non-alcoholic fatty liver disease (NAFLD).
Data Resources:
Searching Medline (1994-2002) and Chinese Medical Journals Index (1998- 2002) for articles on NAFLD.
Results:
NAFLD is a new and challenging field with increasing recognition although its pathogenesis is poorly understood. "Two hits" hypothesis is still the leading theory guiding current research.
Conclusions:
Genetic study is a promising way that might lead to breakthrough in NAFLD research. NAFLD study in China is at an initial stage and there is a long way to go.
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