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Chronic bronchitis in an elderly population
Peter Lange1, Jan Parner, Eva Prescott
1Copenhagen City Heart Study, Bispebjerg University Hospital, Copenhagen NV, Denmark. peter.lange@hh.hosp.dk
Insights
Chronic bronchitis is common in older adults, affecting 13% of women and 18.6% of men. This condition significantly increases the risk of respiratory infections and mortality from various causes.
Area of Science:
- Gerontology
- Pulmonology
- Epidemiology
Background:
- Chronic bronchitis prevalence and prognostic implications in elderly individuals (≥65 years) were investigated.
- Data originated from The Copenhagen City Heart Study.
Purpose of the Study:
- To determine the prevalence of chronic bronchitis in the elderly population.
- To identify prognostic implications of chronic bronchitis on survival and respiratory health.
Main Methods:
- Longitudinal study analyzing data from 1976-1994 with up to 12 years of survival follow-up.
- Included approximately 3,700 elderly participants (mean age 76 years).
- Utilized logistic and Cox regression analyses to assess predictors and survival outcomes.
Main Results:
- Prevalence of chronic bronchitis was 13.0% in women and 18.6% in men.
- Key predictors included male gender, smoking history, dust/fume exposure, childhood chest infections, recent chest infections, and high alcohol consumption.
- Chronic bronchitis significantly predicted increased risk of respiratory infections, all-cause mortality (HR=1.3), benign respiratory diseases (HR=2.0), obstructive lung disease (HR=2.5), and lung cancer (HR=2.0).
Conclusions:
- Chronic bronchitis is a prevalent condition in the elderly population.
- The condition carries significant prognostic implications for respiratory health and overall survival.
Background:
in order to describe the prevalence and prognostic implications of chronic bronchitis in individuals 65 years or older we analysed data from The Copenhagen City Heart Study.
Methods:
the population was studied in 1976-1978 resurveyed in 1981-1983 and 1991-1994 and followed with regard to survival for up to 12 years. Approximately 3,700 elderly participants with a mean age of 76 years were available for analyses.
Results:
the prevalence of chronic bronchitis was 13.0% in women and 18.6% in men. Multiple logistic regression yielded the following predictors for chronic bronchitis: male gender (odds ratio with 95% confidence interval = 1.1 (0.9-1.3)), previous smoking odds ratio = 1.7 (1.2-2.2), present smoking odds ratio = 2.1 (2.1-3.8), previous exposure to dusts and fumes (odds ratio = 2.2 (1.7-2.7)), chest infections in childhood (odds ratio = 2.1 (1.6-2.9)), more than 6 chest infections in previous 10 years (odds ratio = 6.2 (4.1-9.2)) and alcohol consumption of more than 3 drinks a day (odds ratio = 1.8 (1.3-2.3)). Chronic bronchitis was a significant predictor of both subsequent respiratory infections and survival. After adjustment for age, smoking and lung function, a Cox regression showed that chronic bronchitis was significantly related to mortality from all causes with a hazard ratio with 95% confidence interval = 1.3 (1.1-1.4), all benign respiratory diseases (hazard ratio = 2.0 (1.6-2.7)), obstructive lung disease (hazard ratio = 2.5 (1.7-3.6)) and lung cancer (hazard ratio = 2.0 (1.4-2.9)).
Conclusions:
in an elderly population, chronic bronchitis is a prevalent condition with important prognostic implications.
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