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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
09:02

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

Published on: November 26, 2018

Thymic function and immunoglobulin mutation genotype in B-cell chronic lymphocytic leukemia patients

Elena Nardini1, Francesca Neri, Elisa Vicenzi

  • 1Department of Experimental Oncology, Molecular Targeting Unit, National Cancer Institute, Via Venezian 1, 20133 Milan, Italy.

International Journal of Cancer
|November 6, 2003
PubMed
Summary

Signal joint T-cell receptor excision circles (sjTRECs) are decreased in most B-cell chronic lymphocytic leukemia (B-CLL) patients, suggesting thymus dysfunction contributes to immune system dysregulation in B-CLL.

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