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Updated: Aug 30, 2026

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Catalytic, asymmetric synthesis of cyanohydrin ethyl carbonates
Yuri N Belokon'1, A John Blacker, Lisa A Clutterbuck
1A.N. Nesmeyanov Institute of Organo-Element Compounds, Russian Academy of Sciences, 117813, Moscow, Vavilov 28, Russian Federation.
Abstract:
[reaction: see text] The bimetallic titanium complex [(salen)TiO](2), where salen is the ligand derived from (R,R)-cyclohexanediamine and 3,5-di-tert-butyl-salicylaldehyde, has been shown to catalyze the asymmetric addition of ethyl cyanoformate to aldehydes leading to cyanohydrin carbonates with high enantiomeric excesses.
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