Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative analysis of sinoatrial node using Doppler tissue images.

Shukui Zhao1, De-yu Li, Yi Zheng

  • 1Biomedical Engineering Center, Sichuan University, Chengdu, Sichuan, China.

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
|November 12, 2003
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dimerization of PHGDH via the catalytic unit is essential for its enzymatic function.

The Journal of biological chemistry·2021
Same author

Identification of an intraocular microbiota.

Cell discovery·2021
Same author

Application of diffusion kurtosis tensor MR imaging in characterization of renal cell carcinomas with different pathological types and grades.

Cancer imaging : the official publication of the International Cancer Imaging Society·2021
Same author

A Novel Six-Gene-Based Prognostic Model Predicts Survival and Clinical Risk Score for Gastric Cancer.

Frontiers in genetics·2021
Same author

The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses.

Frontiers in microbiology·2021
Same author

Simple and efficient one-pot multi-step strategy for the synthesis of 2-substituted (1,2,5-triarylpyrrolo[3,2-c]pyridin-3-yl)-N-arylacetamide derivatives in water.

Organic & biomolecular chemistry·2021

Researchers developed a new method to analyze the sinoatrial node (SAN) using Doppler tissue imaging (DTI). This technique quantitatively measures SAN tissue acceleration, revealing its correlation with cardiac electrical activity and the cardiac cycle.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • The sinoatrial node (SAN) is crucial for initiating cardiac electrical activity.
  • Quantitative analysis of SAN mechanical function has been limited.
  • Understanding SAN dynamics is key to diagnosing cardiac conduction disorders.

Purpose of the Study:

  • To develop and validate a novel method for quantitative analysis of the sinoatrial node (SAN).
  • To investigate the relationship between SAN mechanical activity and electrical cardiac activity using Doppler tissue imaging (DTI).

Main Methods:

  • Acquisition of DTI of the SAN using an intracardiac catheter inserted via the superior vena cava in an in vivo setting.
  • Extraction and quantitative analysis of tissue acceleration from sequential DTI images covering a complete SAN excitation cycle.

Related Experiment Videos

  • Comparison of the derived time-acceleration curve with the electrocardiogram (ECG).

    • Main Results:

    • The study successfully implemented DTI for quantitative SAN analysis.
    • The time-acceleration curve derived from SAN tissue movement closely resembled the ECG curve.
    • This demonstrates a significant correlation between SAN mechanical tissue movement and electrical cardiac activity across the cardiac cycle.

    Conclusions:

    • The developed DTI method provides a quantitative assessment of SAN mechanical function.
    • SAN tissue acceleration is directly linked to electrical cardiac activity and cardiac cycle phases.
    • This technique holds potential for characterizing local cardiac activity and studying conduction pathways.