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Related Experiment Videos

Trace explosive detection in aqueous samples by solid-phase extraction ion mobility spectrometry (SPE-IMS).

Tricia L Buxton1, Peter de B Harrington

  • 1Ohio University, Center for Intelligent Chemical Instrumentation, Department of Chemistry and Biochemistry, Clippinger Laboratories, Athens, Ohio 45701-2979, USA.

Applied Spectroscopy
|November 13, 2003
PubMed
Summary

Solid-phase extraction coupled with ion mobility spectrometry (IMS) enables sensitive detection of explosives in water. This method achieves trace-level detection down to one part per trillion, improving environmental analysis.

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Area of Science:

  • Analytical Chemistry
  • Environmental Science
  • Forensic Science

Background:

  • Ion mobility spectrometry (IMS) is utilized by law enforcement for detecting explosives, drugs, and chemical agents.
  • IMS offers rapid analysis, high sensitivity (parts per billion), and suitability for on-site environmental monitoring.
  • Direct analysis of trace explosives in water is challenging due to low concentrations and interfering substances.

Purpose of the Study:

  • To develop and validate a method for the sensitive detection of trace explosives in water samples.
  • To enhance the capabilities of ion mobility spectrometry for environmental analysis of explosive residues.

Main Methods:

  • Solid-phase extraction (SPE) was employed for pre-concentration of analytes and removal of interferents from water samples.

Related Experiment Videos

  • Commercially available SPE disks were used, and after extraction, they were directly inserted into the ion mobility spectrometer.
  • Thermal desorption from the SPE disk was used to introduce analytes into the IMS for analysis.
  • Data acquisition was performed using LabVIEW software, and SIMPLISMA was applied for data analysis.

    • Main Results:

    • The coupled SPE-IMS technique significantly improved detection limits for explosives in water.
    • Detection concentrations as low as one part per trillion (ppt) were achieved using a Barringer Ionscan 350.
    • The method demonstrated effectiveness in identifying trace amounts of explosives, overcoming limitations of direct analysis.

    Conclusions:

    • Coupling solid-phase extraction with ion mobility spectrometry is a powerful approach for the trace analysis of explosives in water.
    • This technique enhances sensitivity and simplifies sample preparation, making on-site environmental detection more feasible.
    • The study highlights the potential of SPE-IMS for improved forensic and environmental monitoring of explosive residues.