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Related Experiment Videos

Early multicenter experience with a noninvasive expandable prosthesis.

Michael D Neel1, Ross M Wilkins, Bhaskar N Rao

  • 1St Jude Children's Hospital, Memphis TN, USA. mneel@wnm.net

Clinical Orthopaedics and Related Research
|November 13, 2003
PubMed
Summary
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A novel noninvasive expandable prosthesis, the Phenix prosthesis, aids limb length equality in pediatric osteosarcoma patients after surgery. Early results show promising functional outcomes and significant lengthening capabilities.

Area of Science:

  • Orthopedic Surgery
  • Pediatric Oncology
  • Biomedical Engineering

Background:

  • Limb salvage surgery in pediatric patients with osteosarcoma presents challenges in maintaining limb length equality.
  • Existing prosthetic solutions may have limitations in accommodating growth in skeletally immature individuals.

Purpose of the Study:

  • To evaluate the safety and efficacy of the Phenix prosthesis, a noninvasive expandable implant, in pediatric patients undergoing limb salvage surgery for osteosarcoma.
  • To assess the functional outcomes and lengthening capabilities of this novel expandable prosthesis.

Main Methods:

  • Eighteen Phenix prostheses were implanted in 15 pediatric patients between 1998 and 2001 for osteosarcoma around the knee.
  • Sixty expansions were performed, with an average of 8.5 mm gained per lengthening.

Related Experiment Videos

  • Follow-up averaged 21.5 months, with functional scores assessed using the Musculoskeletal Tumor Society (MSTS) system.

    • Main Results:

    • An average MSTS functional score of 90% was achieved.
    • The prosthesis allowed for an average lengthening of 8.5 mm per expansion.
    • Eight revisions were necessary due to stem fracture or loosening; one amputation occurred due to arterial thrombosis.

    Conclusions:

    • The Phenix prosthesis is a unique, expandable custom implant offering benefits for maintaining limb length equality in growing pediatric patients.
    • While early outcomes are promising, further long-term data on structural integrity are needed.
    • This technology holds potential for treating malignant bone tumors and other conditions requiring serial limb length equalization or spinal deformity correction.