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Experiences with a new nonbiodegradable hydrogel (Aquamid): a pilot study.
Wilse de Cássia Novaes1, Agnes Berg
1Plastikkirurgiska Kliniken, Stockholm, Sweden.
Aesthetic Plastic Surgery
|November 13, 2003
Summary
Aquamid, a new injectable soft-tissue filler composed of polyacrylamide and water, shows nearly 100% patient satisfaction for aesthetic corrections. This non-biodegradable filler offers a promising long-lasting solution with minimal side effects.
Area of Science:
- Dermatology
- Plastic Surgery
- Biomaterials Science
Background:
- Aquamid is a novel soft-tissue filler featuring a particle-free composition and high water content.
- It utilizes a patented
- In line Cross-Linking Technology
- (ILX Technology)
- for production.
- The gel consists of 2.5% polyacrylamide (PAAG) and 97.5% water, offering stability, homogeneity, and optimal viscoelastic properties.
Purpose of the Study:
- To evaluate the clinical experience and patient outcomes with Aquamid in aesthetic and medical applications.
- To assess the efficacy and safety profile of Aquamid as a long-lasting soft-tissue filler.
Main Methods:
- A pilot study involving 59 subjects treated with 77 doses of Aquamid.
- Procedures included lip augmentation, cheekbone enlargement, and correction of nasolabial folds, glabella, and chin.
- A follow-up period of 9 months (range: 2-16 months) was conducted to monitor outcomes and side effects.
Main Results:
- Lip augmentation was the most common procedure (72%), with high satisfaction reported across age groups.
- Cheekbone enlargement accounted for 13% of cases, with other facial augmentations comprising 5% each.
- Nearly 100% patient satisfaction with aesthetic results was observed, with minimal short-term or long-term side effects.
Conclusions:
- Aquamid is a promising, long-lasting soft-tissue filler with high patient satisfaction and a favorable safety profile.
- Its ease of use and lack of need for pretesting are advantageous.
- Administration requires qualified and experienced personnel, emphasizing the importance of proper technique and adherence to guidelines.