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Nephrogenic fibrosing dermopathy: two pediatric cases
Farhana Jan1, Jennifer M Segal, Jonathan Dyer
1Department of Dermatology, University of Cincinnati, Cincinnati, Ohio, USA.
The Journal of Pediatrics
|November 15, 2003
Summary
Nephrogenic fibrosing dermopathy (NFD) is a rare skin condition affecting individuals with kidney dysfunction. This report details two pediatric cases, highlighting extensive skin hardening and scleromyxedema-like changes.
Area of Science:
- Dermatology
- Nephrology
- Pathology
Background:
- Nephrogenic fibrosing dermopathy (NFD) is a rare condition associated with renal dysfunction.
- First described in 2000, NFD presents with significant skin hardening.
Observation:
- Two pediatric cases of NFD are presented.
- Patients exhibited extensive skin hardening.
Findings:
- Histopathologic examination revealed a scleromyxedema-like condition.
- NFD is linked to underlying renal dysfunction in affected individuals.
Implications:
- This report expands the understanding of NFD in pediatric populations.
- Further research is needed to elucidate the pathogenesis and treatment of NFD.