Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A model for intracortical visual prosthesis research.

Philip Troyk1, Martin Bak, Joshua Berg

  • 1Pritzker Institute of Biomedical Science and Engineering, Illinois Institute of Technology, Chicago, IL 60616-3793, USA. troyk@iit.edu

Artificial Organs
|November 18, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Mind and Movement clinic: developing a new integrated cognitive-neuropsychiatric service for Lewy body dementia.

Irish journal of psychological medicine·2026
Same author

Arrhythmias in Fontan.

Heart rhythm·2026
Same author

Beyond TG‑43: A PRISMA-based systematic review on model-based dose-calculation algorithms in brachytherapy.

Journal of applied clinical medical physics·2026
Same author

"You thrive where you are:" Experiences of neighborhood built environments, mental health and wellbeing among residents of disinvested neighborhoods.

Health & place·2026
Same author

Multi-omic analysis of human PHACTR1 signaling networks.

Communications biology·2026
Same author

A novel LC-MS/MS multi-group method for simultaneous determination of antimicrobial residues in legume-based alternative proteins.

NPJ science of food·2026

This study introduces a novel animal model for visual prosthesis research, overcoming limitations of linguistic reporting through advanced psychophysical testing. The model enables investigation of cortical visual prosthetics by training macaques to perceive electrical stimulation.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Ophthalmology

Background:

  • Animal models are crucial for visual prosthesis research but lack linguistic feedback for perceptual reporting.
  • Traditional methods limit assessing the functional outcomes of visual prosthetics in non-human subjects.
  • Bridging the gap between neural activity and subjective perception in animal models remains a challenge.

Purpose of the Study:

  • To develop and validate a novel animal model for cortical visual prosthesis research.
  • To overcome the limitations of linguistic reporting in animal models using psychophysical techniques.
  • To investigate stimulation strategies for a multichannel sensory cortical interface.

Main Methods:

  • Chronic implantation of 152 intracortical microelectrodes in area V1 of a macaque.

Related Experiment Videos

  • Integration of receptive field mapping and eye-tracking for a reward-based training paradigm.
  • Training the macaque to perform a memory saccade task using electrically induced phosphenes.

    • Main Results:

    • Successfully trained a macaque to utilize electrically induced phosphenes for a psychophysical task.
    • Demonstrated the feasibility of using a non-linguistic animal model for visual prosthesis research.
    • Established a foundation for investigating advanced stimulation strategies in a primate model.

    Conclusions:

    • Novel psychophysical testing can compensate for the lack of linguistic reports in animal models for visual prosthesis research.
    • This validated animal model provides a platform for advancing the development of cortical visual prosthetics.
    • The model facilitates the investigation of stimulation strategies for future multichannel sensory cortical interfaces.