Related Experiment Video
Updated: Aug 30, 2026

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
Published on: January 29, 2011
Evaluation of a new combined SpO2/PtcCO2 sensor in anaesthetized paediatric patients
Alexander Dullenkopf1, Stefano Di Bernardo, Felix Berger
1Departments of Anaesthesia Cardiology, University Children's Hospital, Zurich, Switzerland. alex.dullenkopf@kispi.unizh.ch
Background:
The recently introduced TOSCA monitor (Linde Medical Sensors AG, Basel, Switzerland) combines pulse oximetry (SpO2) and transcutaneous PCO2 (PtcCO2) monitoring in a single ear sensor. The aim of the present study was to evaluate accuracy of the TOSCA monitor to estimate SaO2 and PaCO2 in anaesthetized children.
Methods:
With approval of the hospital ethical committee and after obtaining informed parental consent, the TOSCA sensor was attached to one ear lobe of anaesthetized children in whom arterial access was established for cardiac catheterization or invasive blood pressure monitoring. SpO and PtcCO2 as well as SpO and PECO2 values from the anaesthesia monitoring (AS5; Datex-Ohmeda, Helsinki, Finland) were compared with SaO2 and PaCO2 values from arterial blood gas analysis. Corresponding data were compared using Bland Altman bias analysis.
Results:
A total of 111 blood samples were taken from 60 children (median age: 4.41 years; 0.35-16.13 years). SaO2 values ranged from 63 to 100% (median: 98.7%), PaCO2 ranged from 3.8 to 7.3 kPa (median: 4.6 kPa). Mean difference (+/-2 sd) between PaCO2 and PtcCO2 was -0.035 kPa (+/-0.74 kPa), between PaCO2 and PECO2 0.002 kPa (0.73 kPa), respectively (1 kPa = 7.3 mmHg). Bias and precision between SaO2 and SpO was -0.63% (+/-2.77%) and 0.13% (+/-4.52%) between SaO2 and SpO.
Conclusions:
In anaesthetized children, the TOSCA ear sensor allows estimation of SaO2 and PaCO2, comparable in accuracy to endtidal capnometry and finger pulse oximetry. This makes the TOSCA monitor a helpful add-on to respiratory monitoring in anaesthetized children, in situations, in which endtidal capnometry is unreliable or difficult to establish.
Related Concept Videos
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
Guidelines For Measuring Vital Signs
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.

