[Technology and analysis of "Askoeziuofito" tablets]

Area of Science:

• Pharmacognosy
• Pharmaceutical Technology

Background:

• Echinacea purpurea is a medicinal plant with potential health benefits.
• Ascorbic acid (Vitamin C) is a vital nutrient with antioxidant properties.
• Combining these in a chewable tablet format offers a convenient delivery method.

Purpose of the Study:

• To develop and optimize the technology for producing chewable tablets containing Echinacea purpurea liquid extract and ascorbic acid.
• To establish analytical methods for quality control.
• To evaluate the stability of the formulated tablets.

Main Methods:

• Tablet formulation using a condensation method.
• Evaluation of the influence of excipients on tableting properties.
• Analysis of pressing characteristics of tablet mixtures.
• Quality control assessments including appearance, average tablet mass, hardness, disintegration time, and ascorbic acid release rate.
• Identification and quantification of key compounds like ascorbic acid, ferments, and hydroxycinnamic acids.

Main Results:

• A viable technology for producing Echinacea purpurea and ascorbic acid chewable tablets was established.
• The impact of various excipients on tablet quality was determined.
• Technological parameters such as hardness and disintegration time were optimized.
• Stability studies confirmed the integrity of the active ingredients.
• The identity and quantity of ascorbic acid and chicory acid were successfully quantified.

Conclusions:

• The developed chewable tablets, named "Askoeziuofito", represent a stable and high-quality phytochemical preparation.
• The study successfully created a novel dosage form combining the benefits of Echinacea purpurea and ascorbic acid.
• The established analytical methods provide a basis for future quality control of this new product.