[Immediate type allergies due to metal - nickel]
Related Experiment Video
Updated: Aug 30, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
V van Kampen1, R Merget, T Brüning
1Berufsgenossenschaftliches Forschungsinstitut für Arbeitsmedizin, Institut der Ruhr-Universität Bochum. kampen@bgfa.de
Abstract:
Occupational allergies of the immediate type due to metals, which are predominantly caused by nickel, platinum, chromium and cobalt, are rather rare. The present paper reviews the results of the evaluation of literature data concerning the occupational airway sensitization due to nickel, which is used in many different industrial fields - especially in the electroplating industry. Cases of specific airway sensizitation caused by nickel are verified by a number of studies, predominantly case histories. In conclusion, there is sufficient evidence that nickel may cause IgE-mediated hypersensitivity with typical symptoms.
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