[Age factors in architectonics of the splenic arterial vessels]

Spleen of 86 people of different ages was examined using the roentgenoanatomical, macromicroscopical, histological, morphometric and variation-statistical methods. It was established that, starting from the first mature age there was a steady reduction of the area occupied by arterial vessels, which reached its minimal value in senile age and in long-livers. In senescent persons, the atrophy of white and red pulp was established with a concomitant increase in spleen stromal elements content. The changes in the ratios of spleen tissue elements define the dynamics of age-related changes of its functions (including the immune function). In elderly and senile age these changes seem to be related with the reduction of adaptation capacities of the intraorgan arterial bed of the spleen.