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Fat detection in gallbladder carcinoma with extensive xanthogranulomatous change demonstrated by chemical shift MR
T Nakayama1, K Yoshimitsu, H Irie
1Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku Fukuoka 812-8582, Japan.
Abstract:
We present a case of gallbladder carcinoma, in which fat was detected on dual-echo chemical shift magnetic resonance imaging (MRI). Histologic analysis showed poorly differentiated adenocarcinoma associated with massive xanthogranulomatous change. Sudan IV staining successfully confirmed the presence of fat within the interstitial histiocytes. Although rare, gallbladder carcinoma with xanthogranulomatous change should be included in the differential diagnosis of fatty tumor involving the region of the liver as observed on chemical shift MRI.

