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Bead Based Multiplex Assay for Analysis of Tear Cytokine Profiles
Published on: October 13, 2017
Tears in health and disease
1Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK. john.tiffany@eye.ox.ac.uk
Eye (London, England)
|November 25, 2003
Summary
This review examines normal tear function and how diseases alter tear composition and physical performance. Further research is needed to develop specific diagnostic tests for clinical use.
Area of Science:
- Ophthalmology
- Tear Film Physiology
Background:
- Tear film is crucial for ocular surface health.
- Disease can significantly alter tear composition and function.
Purpose of the Study:
- To review normal tear film physiology.
- To survey disease-induced changes in tear composition and physical performance.
Main Methods:
- Literature review of factors affecting normal tear function.
- Survey of reported changes in tear composition and physical properties.
- Listing of major tear test categories.
Main Results:
- Disease-associated changes in measurable tear functions are described.
- Knowledge gaps in tear film research are identified.
Conclusions:
- Existing techniques can assess normal and diseased tears.
- Further development is required for clinical application and specificity of diagnostic tests.
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