Related Experiment Video
Updated: Jul 29, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Applications of three dimensional echocardiography beyond the left ventricle: other chambers and structural detail
F H Sheehan1, E L Bolson, J A McDonald
1University of Washington, Seattle, WA, USA. sheehan@u.washington.edu
Insights
This study presents a quantitative three-dimensional echocardiography (3D echo) system for comprehensive heart analysis. The advanced 3D echo tool allows detailed assessment of all four heart chambers and associated structures.
Area of Science:
- Cardiology
- Medical Imaging
- Biomedical Engineering
Background:
- Quantitative analysis of cardiac structures is crucial for diagnosing and managing cardiovascular diseases.
- Existing echocardiography methods may have limitations in fully assessing complex 3D cardiac anatomy and function.
Purpose of the Study:
- To introduce and validate a novel system for quantitative three-dimensional echocardiography (3D echo).
- To enable comprehensive analysis of all four heart chambers, valves, and associated cardiac structures.
Main Methods:
- Image acquisition using freehand scanning and magnetic field tracking.
- Manual tracing of cardiac structure borders followed by reconstruction using subdivision surfaces and Fourier series.
- Anatomic labeling for precise identification of various cardiac components.
Main Results:
- The system allows for the reconstruction of all four heart chambers, valves, and associated structures.
- Quantitative determination of dimensions, shape, and function of cardiac components.
- Assessment of spatial relationships between cardiac structures, including distances and angles.
Conclusions:
- The developed 3D echo system offers enhanced capability and flexibility for clinical applications.
- Potential applications include modeling heart motion, investigating mitral regurgitation mechanisms, and tracking left ventricular remodeling.
Abstract:
The authors' system for quantitative three-dimensional echocardiography (3D echo) now enables analysis of all four heart chambers, valves and associated structures. After image acquisition using freehand scanning and a magnetic field tracking device, the borders of cardiac structures are manually traced. Chambers are reconstructed with a piecewise smooth subdivision surface. The mitral and tricuspid annuli are fitted using a 4 term Fourier series. Other valves and orifices are reconstructed as ellipses. Anatomic labeling enables identification of the chordae, coronary sinus, intervalvular fibrosa, septum, and right and left ventricular apex. The dimensions, shape, and function of cardiac components and the spatial relationships between them such as distance and angle can be determined. These methods provide capability and flexibility for clinical applications such as modeling heart motion, investigating the mechanism of functional mitral regurgitation, and tracking left ventricular remodeling.
Related Concept Videos
Chambers of the Heart
Deoxygenated blood from the body is received in the right...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Cardiac Catheterization III: Left Heart Catheterization

