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Supplementing with beta-hydroxy-beta-methylbutyrate (HMB) to build and maintain muscle mass: a review
Tal Alon1, Debasis Bagchi, Harry G Preuss
1Department of Physiology, Medicine and Pathology, Georgetown University Medical Center, Washington, DC 20057, USA.
Abstract:
Beta-hydroxy-beta-methylbutyrate, more commonly referred to as HMB, is derived from the amino acid, leucine, and its keto acid, alpha-ketoisocaproate. In several studies combining HMB supplementation and resistance exercise, researchers have concluded that HMB may play an important role in reducing protein degradation and/or increasing recovery of damaged muscle cells. These actions could be advantageous to all individuals participating in exercise programs and improve the lives of many by overcoming weakness or frailty.
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