Related Experiment Video

Updated: Aug 30, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

[Risk profile and survival in patients with heart failure caused by systolic function. Prospective study with 4-year

Carlos Alberto Solís Olivares1, Carlos Jerjes-Sánchez Díaz, Tamara Archondo Arce

  • 1Hospital General de Zona No. 6, IMSS, Monterrey.

Archivos De Cardiologia De Mexico
|November 26, 2003
PubMed

Insights

This study identifies a high-risk profile for adverse cardiovascular events in patients with systolic left ventricular dysfunction treated in community hospitals. This profile helps prioritize patients for cardiac transplant programs.

Area of Science:

  • Cardiology
  • Heart Failure Research
  • Clinical Prognostics

Context:

  • Current knowledge on systolic left ventricular dysfunction prognosis relies on multicenter trials with strict inclusion criteria.
  • Community hospitals often manage patients with broader characteristics.
  • Understanding prognosis in a real-world setting is crucial for effective patient management.

Purpose:

  • To establish a risk profile for adverse cardiovascular events in community-hospital-based systolic left ventricular dysfunction patients.
  • To determine survival rates in this patient cohort.
  • To identify predictors of poor outcomes.

Summary:

  • A 4-year prospective study followed 110 symptomatic patients (ejection fraction < 40%).
  • Key risk factors identified include age > 65, female gender, hypertension, diabetes mellitus II, ischemic heart disease, NYHA class III/IV, and ventricular tachycardia.
  • Global mortality was 26% over a mean follow-up of 30 months.

Impact:

  • The identified risk profile enables stratification of high-priority patients for cardiac transplant consideration.
  • This research provides valuable insights for managing systolic left ventricular dysfunction outside specialized centers.
  • Facilitates resource allocation and clinical decision-making in community healthcare settings.
Abstract

Related Concept Videos

Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...