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[Gamma knife radiosurgery for trigeminal schwannomas]
En-min Wang1, Bin-jiang Wang, Nan Zhang
1Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200233, China.
Zhonghua Yi Xue Za Zhi
|December 3, 2003
Summary
Gamma Knife (GK) radiosurgery effectively controls small to medium trigeminal schwannomas, with a 91% tumor control rate. This treatment offers a viable option for managing these challenging tumors.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Context:
- Trigeminal schwannomas are rare tumors affecting cranial nerves.
- Gamma Knife (GK) radiosurgery is an advanced treatment modality for brain tumors.
- Evaluating the efficacy of GK for trigeminal schwannomas is crucial for treatment planning.
Purpose:
- To assess the role and outcomes of Gamma Knife (GK) radiosurgery in treating trigeminal schwannomas.
- To determine the tumor control rate and clinical outcomes following GK treatment.
- To identify optimal candidates and dosage for GK radiosurgery in trigeminal schwannoma management.
Summary:
- A review of 38 patients with trigeminal schwannoma treated with GK radiosurgery (1994-2000).
- Mean tumor volume was 9 cm³, with doses ranging from 11-15 Gy at the margin.
- 91% tumor control rate observed in 35 patients followed for a mean of 65 months, with symptom improvement in many cases.
Impact:
- Gamma Knife radiosurgery demonstrates high efficacy in controlling trigeminal schwannoma growth.
- Small and medium-sized tumors are identified as ideal candidates for GK treatment.
- Results support GK as a primary or adjuvant therapy, with a recommended marginal dose of 13-14 Gy.