Related Experiment Videos
Macular hole closure after peribulbar steroid injection
Ioannis Halkiadakis1, Eugenia Pantelia, Nikos Giannakopoulos
1Department of Ophthalmology, General Hospital of Athens, Athens, Greece.
American Journal of Ophthalmology
|December 4, 2003
Summary
Peribulbar corticosteroid injections successfully closed a macular hole in a patient with human leukocyte antigen B*27-associated uveitis. This treatment also resolved inflammation and macular edema, improving visual acuity.
Area of Science:
- Ophthalmology
- Immunology
Background:
- Anterior uveitis associated with human leukocyte antigen B*27 can lead to ocular complications.
- Macular holes and edema are potential visual impairments in such cases.
Observation:
- A 50-year-old woman with active HLA-B*27 anterior uveitis presented with a macular hole in her right eye and macular edema in her left eye.
- Visual acuity was significantly reduced in both eyes (20/200).
Findings:
- Peribulbar injections of triamcinolone acetonide were administered bilaterally.
- Three months post-injection, visual acuity improved to 20/50 in both eyes.
- Optical coherence tomography confirmed the closure of the macular hole in the right eye.
- Uveitis was in complete remission.
Implications:
- Inflammation and macular edema may play a role in the pathogenesis of macular holes in uveitis patients.
- Treating inflammation and macular edema could potentially lead to macular hole closure.