Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inhibitory functioning in Alzheimer's disease.

Hélène Amieva1, Louise H Phillips, Sergio Della Sala

  • 1Department of Psychology, University of Aberdeen, UK. Helene.Amieva@isped.u-bordeaux2.fr

Brain : a Journal of Neurology
|December 3, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dismantling the mechanism of VR self-compassion training: A two-session controlled trial with active controls.

Behaviour research and therapy·2026
Same author

Heterogeneous trajectories of executive function in clinical Alzheimer's disease: Results from the 3C study.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Functional disability and cognition in relation to residential transitions in older adults: Evidence from three French cohorts, 1988-2018.

The Journal of frailty & aging·2026
Same author

The Use of Silver Fluoride for Oral Health and Well-Being in Aged Care Residents: Protocol for a Cluster Randomized Controlled Trial.

JMIR research protocols·2026
Same author

Autistic Traits and Camouflaging: A Meta-Analysis.

Autism : the international journal of research and practice·2026
Same author

Healthcare Utilization Among Older Adults With Dementia in France: A Comparative Analysis of a Dementia Village and Traditional Nursing Homes.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026
Same journal

Disrupted WWOX-MYC interplay impairs neurogenesis in human brain organoids.

Brain : a journal of neurology·2026
Same journal

SMPD4 deficiency disrupts indirect neurogenesis and neuronal migration in gyrencephalic cortex.

Brain : a journal of neurology·2026
Same journal

Retinal hyper-reflective foci link retinal and cortical pathology in paediatric multiple sclerosis.

Brain : a journal of neurology·2026
Same journal

Two scripts, two pathways: dorsal-ventral biases in post-stroke kana-kanji agraphia.

Brain : a journal of neurology·2026
Same journal

Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.

Brain : a journal of neurology·2026
Same journal

Time to reconsider risk for psychosis?

Brain : a journal of neurology·2026
See all related articles

Alzheimer's disease impacts most inhibitory functions, but not equally. Controlled inhibition is more affected than automatic inhibition, suggesting specific cognitive deficits rather than a general breakdown.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Gerontology

Background:

  • Inhibitory functioning is crucial for various cognitive processes.
  • Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline.
  • Understanding specific cognitive deficits in AD is vital for diagnosis and management.

Purpose of the Study:

  • To review studies on inhibitory functioning in Alzheimer's disease.
  • To determine if AD affects all inhibitory mechanisms equally.
  • To investigate if other cognitive deficits, like slowed processing, contribute to inhibition impairments in AD.

Main Methods:

  • Comprehensive literature review of studies assessing inhibitory functioning in AD.
  • Analysis of inhibitory mechanisms in working memory, attention, and response inhibition.

Related Experiment Videos

  • Meta-analysis of Stroop paradigm studies in AD.

    • Main Results:

    • Most inhibitory mechanisms are affected by AD, but some remain relatively preserved.
    • AD significantly impairs controlled inhibition tasks (e.g., Stroop task).
    • AD has less impact on automatic inhibition tasks (e.g., inhibition of return).

    Conclusions:

    • Inhibitory deficits in AD may not stem from a general breakdown.
    • The distinction between automatic and controlled inhibition is critical for understanding AD's impact.
    • AD's effects on inhibition suggest specific impairments in controlled processes.