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Updated: Aug 30, 2026

A Minimally Invasive Model of Aortic Stenosis in Swine
Published on: October 20, 2023
Functional aortic stenosis diagnosed in fetal period
Kazuya Kawamata1, Ken Watanabe, Yoshihide Chiba
1Department of Perinatology, National Cardiovascular Center, Suita, Osaka, Japan. kkawamat@hsp.ncvc.go.jp
Abstract:
We report a case of fetal congenital heart disease prenatally diagnosed as critical aortic valve stenosis at 25 weeks of gestation. Fetal echocardiography demonstrated severe mitral regurgitation, aortic valve stenosis, hypocontractility of the left ventricle, and showed retrograde flow in the aortic arch like HLHS (hypoplastic left heart syndrome). However, soon after delivery, improvement in the baby's hemodynamics and myocardial contractility were recognized without any treatment.
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