[Risk factors for suspicion of developmental delays at 12 months of age]
R Halpern1, E R Giugliani, C G Victora
1Fundação Federal Faculdade Ciências Médicas Porto Alegre (FFFCMPS), RS, Brazil.
Insights
Developmental delays affect 34% of 12-month-olds in Pelotas, Brazil. Lower income, low birth weight, and shorter breastfeeding duration are significant risk factors for developmental delays.
Area of Science:
- Pediatrics
- Developmental Psychology
- Public Health
Background:
- Developmental delays pose a significant public health challenge globally.
- Early identification and intervention are crucial for improving child development outcomes.
- Understanding risk factors is essential for targeted prevention strategies.
Purpose of the Study:
- To determine the prevalence of positive screening tests for developmental delays in a Brazilian birth cohort.
- To identify socioeconomic, environmental, and health-related risk factors associated with developmental delays.
Main Methods:
- A 20% sample (1,363 children) of a 1993 Pelotas, Brazil birth cohort was assessed at 12 months using the Denver II Test.
- Children failing two or more Denver II items were considered to have a potential developmental delay.
- Multivariate conditional logistic regression was used to analyze risk factors, controlling for confounding variables.
Main Results:
- 34% of children screened positive for developmental delays at 12 months.
- Key risk factors included lower family income (OR=1.5), very low birth weight (OR=4.0), preterm birth (OR=1.6), more than three siblings (OR=1.9), and limited breastfeeding (OR=1.6-1.9).
- Children with weight-for-age below -2 z-scores at six months had a 10-fold increased risk (OR=10.0) of developmental delay.
Conclusions:
- Developmental delays have a multifactorial etiology with a cumulative risk effect.
- Economically disadvantaged children in this population accumulate multiple risk factors, increasing their vulnerability to developmental deficits.
- Findings highlight the need for integrated social, economic, and health interventions to mitigate developmental delays.
Abstract:
OBJECTIVE: To investigate the prevalence of positive screening test for developmental delays in a cohort of children born in Pelotas, Brazil in 1993, and their risk factors. METHODOLOGY: A sample of 20% (1,363 children) of a cohort of children born in Pelotas, Brazil, was studied at 12 months of age regarding their development. The Denver II Test was used. The children who failed in two or more items of the test were suspected of having development delay. A set of independent variables was chosen taking into account the hierarchical relations between risk factors according to the conceptual framework (socioeconomic, reproductive and environmental, birth conditions, childreńs care, nutrition and morbidity). Analyses were performed using Mantel-Haenszel X2 and multivariate technique through conditional logistic regression, to control for possible confounding. RESULTS: At 12 months of age, 34% (463) of the total of 1,363 children failed in the screening test. After adjusting for possible confounding variables, failure was associated with family lower income children (OR= 1.5), very low birth weight (OR= 4.0), gestational age less than 37 weeks (OR= 1.6), more than three siblings (OR= 1.9), and duration of breastfeeding less than three months (OR=1.6), or no breastfeeding (OR= 1.9). Children who presented weight/age at six months of age less or equal to -2 z score of the reference population presented a risk 10 times greater of having failure in the Denver II Test. CONCLUSIONS: This study reinforces the multiple etiology of development delays and the concept of cumulative risk effect. In this population those who are economically disadvantaged accumulate risk factors (social, economic and environmental) that may render to deficits in their development.
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