Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Inhalation of nitric oxide - dependence: case report]

W B Carvalho1, T Matsumoto, S M Horita

  • 1Universidade Federal de São Paulo, SP, Brazil.

Jornal De Pediatria
|December 4, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Flowering phenology in species of Chamaecrista (L.) Moench: temporal generation of functionally enantiostylous dimorphic individuals.

Plant biology (Stuttgart, Germany)·2026
Same author

When hunger is greater than the beak: Guira Tanager (Aves, Thraupidae) strategy to optimize frugivory.

Brazilian journal of biology = Revista brasleira de biologia·2022
Same author

Seed dispersal of the palm Acrocomia aculeata by the Blue-and-Yellow Macaw (Ara ararauna).

Brazilian journal of biology = Revista brasleira de biologia·2021
Same author

How do leaf wetting events affect gas exchange and leaf lifespan of plants from seasonally dry tropical vegetation?

Plant biology (Stuttgart, Germany)·2019
Same author

Isolation from natural habitat reduces yield and quality of passion fruit.

Plant biology (Stuttgart, Germany)·2018
Same author

Functional dimorphic enantiostyly in monomorphic enantiostylous species of the subtribe Cassiinae (Fabaceae-Caesalpinioideae).

Plant biology (Stuttgart, Germany)·2018
Same journal

Acetaminophen versus Ibuprofen for the management of hemodynamically significant patent ductus arteriosus in very low birth weight infants: randomized trial.

Jornal de pediatria·2026
Same journal

Cross-cultural adaptation into Brazilian Portuguese of an international questionnaire for the assessment of cardiopulmonary resuscitation knowledge among adolescents.

Jornal de pediatria·2026
Same journal

Evaluation of ChatGPT's reliability in answering questions about short stature and growth failure.

Jornal de pediatria·2026
Same journal

Validity of the Khamis-Roche method, relative to bone age, in Portuguese children and adolescents from 11 to 15 years.

Jornal de pediatria·2026
Same journal

Urogenital congenital anomalies in children under 9 years: global disease burden analysis and projections, 1990-2021.

Jornal de pediatria·2026
Same journal

Intraventricular hemorrhage in preterm newborns: a multicenter study in four Brazilian hospitals.

Jornal de pediatria·2026
See all related articles

Pulmonary hypertension rebound can occur after stopping inhaled nitric oxide (NO) treatment in pediatric acute respiratory distress syndrome (ARDS) patients. Careful monitoring is crucial during NO withdrawal to manage potential hemodynamic instability.

Area of Science:

  • Pediatric Critical Care Medicine
  • Cardiovascular Physiology

Background:

  • Acute respiratory distress syndrome (ARDS) can lead to pulmonary hypertension.
  • Inhaled nitric oxide (NO) is used to treat pulmonary hypertension in ARDS.
  • The potential for rebound pulmonary hypertension after NO withdrawal is a clinical concern.

Purpose of the Study:

  • To describe the hemodynamic response, specifically pulmonary hypertension rebound, after inhaled NO withdrawal in a pediatric ARDS patient.
  • To highlight the clinical implications of managing inhaled NO therapy in this population.

Main Methods:

  • A case report detailing a pediatric patient with ARDS and pulmonary hypertension.
  • Echocardiography with Doppler was used to monitor pulmonary artery pressure (PAP).
  • Inhaled NO was administered for 21 days, with periods of withdrawal and reintroduction.

Related Experiment Videos

Main Results:

  • Inhaled NO titration initially reduced PAP from 52 mmHg to 44 mmHg.
  • Withdrawal of inhaled NO led to a PAP increase to 55 mmHg, requiring reintroduction.
  • A subsequent attempt at withdrawal after 20 days of treatment caused clinical worsening and increased PAP.

Conclusions:

  • Rebound pulmonary hypertension is a potential complication following inhaled NO withdrawal in pediatric ARDS.
  • Prolonged inhaled NO treatment necessitates careful consideration of withdrawal protocols.
  • This case underscores the importance of vigilant monitoring for hemodynamic changes during inhaled NO discontinuation.