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[Visceral leishmaniasis: clinical and laboratorial aspects]
Antonio C Pastorino1, Cristina M A Jacob, Gabriel W Oselka
1Dep de Pediatria, Universidade de São Paulo, São Paulo, SP. antoniocp@icr.hcnet.usp.br
Jornal De Pediatria
|December 4, 2003
Summary
Visceral leishmaniasis treatment in children significantly improved hematological findings and organ size. Early diagnosis is crucial, especially in non-endemic areas, for effective pediatric visceral leishmaniasis management.
Area of Science:
- Pediatric Infectious Diseases
- Tropical Medicine
- Clinical Parasitology
Context:
- Visceral leishmaniasis (VL) is a serious parasitic disease affecting children.
- Diagnosis and treatment can be challenging in non-endemic regions.
- This study evaluates VL cases in a pediatric hospital outside endemic zones.
Purpose:
- To compare clinical and laboratory data before and after treatment for pediatric visceral leishmaniasis.
- To emphasize the importance of recognizing VL in pediatric patients, even in non-endemic settings.
- To analyze treatment outcomes and patient recovery.
Summary:
- A retrospective study of 78 pediatric patients with visceral leishmaniasis (VL) from 1981-1992.
- Fever and splenomegaly were common presenting symptoms.
- Significant improvements in hemoglobin, platelets, albumin, and organ size were observed post-treatment (P<0.001).
Impact:
- Highlights the need for considering visceral leishmaniasis in pediatric patients presenting with fever and enlarged spleen, particularly those from endemic areas.
- Informs healthcare providers in low-incidence areas about diagnostic and treatment considerations for VL.
- Demonstrates successful treatment outcomes and the importance of timely intervention in pediatric VL cases.