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Comprehensive two-dimensional gas chromatography using liquid nitrogen modulation: set-up and applications.

Matthias Pursch1, Patric Eckerle, Juergen Biel

  • 1Dow Deutschland GmbH & OHG, Analytical Sciences, 77836 Rheinmuenster, Germany. mpursch@dow.com

Journal of Chromatography. A
|December 3, 2003
PubMed
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A new two-jet modulation system enhances comprehensive two-dimensional gas chromatography (GC x GC) for analyzing volatile and non-volatile compounds. This improved system extends operational temperature ranges and broadens GC x GC applications.

Area of Science:

  • Analytical Chemistry
  • Chromatography

Background:

  • Comprehensive two-dimensional gas chromatography (GC x GC) is a powerful separation technique.
  • Existing modulation systems can limit the range of analytes and operational temperatures.

Purpose of the Study:

  • To present an improved modulation system for GC x GC.
  • To extend the applicability of GC x GC to a wider range of volatile and non-volatile compounds.

Main Methods:

  • Development of a novel two-jet modulation system utilizing liquid nitrogen as a cryogen.
  • Incorporation of a valve system for re-heating cooled capillary segments post-modulation.
  • Demonstration of modulation efficiency with volatile compounds like propane and butane.

Main Results:

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  • The new system effectively modulates volatile compounds, expanding the operational temperature range compared to existing methods.
  • Highly efficient analysis of both volatile and non-volatile components is achieved.
  • Successful applications demonstrated for alkenes, gasoline, sulfur-containing hydrocarbons, and volatiles in polymer latex-coated papers.

Conclusions:

  • The improved two-jet modulation system significantly enhances GC x GC capabilities.
  • This advancement broadens the scope of GC x GC analysis for diverse sample types and industries.