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Gelatin sponge closure device versus manual compression after peripheral arterial catheterization procedures
Flavio Castañeda1, James L Swischuk, H Bob Smouse
1Radiology Department, University of Illinois College of Medicine at Peoria, 1 Illini Drive, Box 1649, Peoria, IL 61656, USA. flavio@miit.com
Journal of Vascular and Interventional Radiology : JVIR
|December 5, 2003
Summary
The QuickSeal device significantly reduced time to hemostasis and ambulation compared to manual compression. This innovative hemostasis system offers a safe and effective alternative for interventional radiology procedures.
Area of Science:
- Interventional Radiology
- Vascular Access
- Hemostasis Devices
Background:
- Vascular access closure is critical in interventional radiology.
- Current methods like manual compression can be time-consuming and variable.
Purpose of the Study:
- To compare the safety and efficacy of the QuickSeal system against manual compression.
- Evaluate QuickSeal in peripheral diagnostic and interventional procedures.
Main Methods:
- 141 patients randomized (3:2 device:control ratio).
- Primary endpoints: time to hemostasis (TTH), time to ambulation (TTA), major complications.
- Device group had higher activated clotting time (ACT) thresholds for sheath removal.
Main Results:
- Mean TTH was significantly shorter with QuickSeal (8.2 min vs. 14.12 min, P <.001).
- Mean TTA was shorter (2.7 hrs vs. 7.1 hrs) and time to discharge was reduced (23.8 hrs vs. 43.6 hrs) with QuickSeal.
- No significant difference in major or minor complications between groups.
Conclusions:
- QuickSeal system effectively reduces TTH and TTA.
- The device demonstrates a safety profile comparable to manual compression.
- QuickSeal offers an efficient alternative for vascular access closure in interventional radiology.