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Lyme disease presenting with persistent headache.

James M Moses1, Robyn S Riseberg, Jonathan M Mansbach

  • 1Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 32115, USA.

Pediatrics
|December 5, 2003
PubMed
Summary
This summary is machine-generated.

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Increased intracranial pressure (ICP) is a rare Lyme disease complication. Early consideration of Lyme disease is crucial for patients with persistent headaches and signs of ICP in endemic regions to prevent potential blindness.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Increased intracranial pressure (ICP) is an uncommon manifestation of Lyme disease.
  • Neuroborreliosis, the neurological form of Lyme disease, can present with varied symptoms.
  • Untreated ICP associated with neuroborreliosis poses a risk of vision loss.

Observation:

  • Two cases are presented involving patients from Lyme-endemic areas.
  • Initial symptoms included persistent headache, nausea, and vomiting.

Findings:

  • Both patients exhibited elevated intracranial pressure.
  • Cerebrospinal fluid analysis revealed mild pleocytosis and positive Lyme titers.
  • Neuroborreliosis was confirmed as the underlying cause.

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Implications:

  • Prompt recognition of Lyme disease is vital in patients with unexplained headaches and signs of increased ICP.
  • Early diagnosis and treatment of neuroborreliosis can prevent severe complications such as blindness.
  • Clinicians in endemic areas should maintain a high index of suspicion for Lyme disease.