Related Experiment Video
Updated: Aug 29, 2026

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
Published on: August 9, 2024
Functional outcome following Botulinum toxin A injection to reduce spastic equinus in adults with traumatic brain
Jimy Fock1, Mary P Galea, Barry C Stillman
1Brighton Rehabilitation Centre, Victoria, Australia.
Primary Objective:
The aim of this study was to assess the effect of Botulinum toxin A in the management of spastic equinus resulting from traumatic brain injury.
Research Design:
A before-after intervention design was used without controls.
Methods And Procedures:
Subjects were seven patients suffering from traumatic brain injury of average duration 14 (4-38) months as a result of motor vehicle trauma, who had spastic equinus interfering with gait.
Experimental Intervention:
The patients were treated with injections of Botulinum toxin A into the spastic calf muscles: gastrocnemius, soleus and tibialis posterior. Assessments were made pre-injection and at 2 weeks and 3 months post-injection.
Main Outcome And Results:
At the end of the 3-month period, all patients showed a significant improvement in gait velocity, cadence and stride length.
Conclusions:
The findings suggest that Botulinum toxin A may be useful in the management of spastic equinus following traumatic brain injury.
Related Concept Videos
Skeletal Muscle Relaxants: Therapeutic Uses
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Botulism
