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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Incidence and Factors Associated With Hospitalizations for Urinary Tract Infections Among Older People Residing in
Yohanes A Wondimkun1, Maria C Inacio2, Noleen Bennett3
1University of South Australia, UniSA Allied Health and Human Performance, Adelaide, SA, Australia.
Objectives:
This study examined the incidence of hospitalizations for urinary tract infections (UTIs) and associated factors among residents of long-term care facilities (LTCFs) during the first 12 months of their LTCF stay.
Design:
Population-based retrospective cohort study.
Setting And Participants:
This study included people aged ≥65 years who first entered an LTCF between 2015 and 2018 using data from the Registry of Senior Australians National Historical Cohort.
Methods:
The cumulative incidence of hospitalizations of UTI in the 12 months following LTCF entry was evaluated. Individual, facility, medicine, and service utilization-related factors associated with hospitalizations for UTIs were investigated. A Fine-Gray model was used to estimate subdistribution hazard ratios (sHRs) and 95% CIs.
Results:
Of the 180,858 people included from 2464 LTCFs, 59.7% (n = 107,914) were female, with a median age of 85 years. The cumulative incidence of hospitalizations for UTIs in the 12 months after LTCF entry was 3.7% (95% CI 3.7-3.8). Factors associated with a higher rate of hospitalizations for UTIs included long-term urinary catheter use (sHR 3.39, 95% CI 3.16-3.65), history of hospitalizations with UTI (sHR 2.33, 95% CI 2.21-2.46), preferred language other than English (sHR 1.38, 95% CI 1.28-1.48), diabetes (sHR 1.29, 95% CI 1.22-1.37), high (sHR 1.30, 95% CI 1.19-1.41) or medium (sHR 1.21, 95% CI 1.11-1.32) need for assistance with activities of daily living, cerebrovascular disease (sHR 1.14, 95% CI 1.08-1.20), and urinary incontinence (sHR 1.08, 95% CI 1.01-1.15).
Conclusions And Implications:
A considerable burden of UTI-associated hospitalizations was observed in Australian LTCFs, which can be minimized through implementing effective UTI prevention, detection, and management strategies.
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