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Related Experiment Videos

Atrioventricular conduction variability in coronary patients.

Miha Arnol1, Vito Starc, Rado Starc

  • 1Institute of Physiology, School of Medicine, University of Ljubljana, Slovenia. miha.arnol@mf.uni-lj.si

Journal of Electrocardiology
|December 9, 2003
PubMed
Summary

Coronary artery disease reduces atrioventricular (AV) conduction variability. Patients with stable coronary artery disease showed decreased PR interval variability, indicating potential conduction issues.

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Internal Medicine

Background:

  • Atrioventricular (AV) conduction variability is documented in healthy individuals.
  • Data on AV conduction variability in coronary artery disease patients are limited.

Purpose of the Study:

  • To assess atrioventricular (AV) conduction variability in patients with stable coronary artery disease.
  • To compare AV conduction variability between coronary artery disease patients and healthy controls.

Main Methods:

  • Measured beat-to-beat PR interval variability using 5-minute resting high-resolution electrocardiogram recordings.
  • Included 30 men with stable coronary artery disease (effort angina) and 30 age-matched controls.
  • Assessed coronary artery disease severity via coronary angiography.

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Main Results:

  • Coronary patients exhibited significantly lower PR interval variability than controls (P <.001).
  • The relative PR variability (PRPP) index was significantly higher in coronary patients (P =.001).
  • PRPP index correlated with the degree of coronary artery disease.

Conclusions:

  • Stable coronary artery disease is linked to diminished beat-to-beat fluctuations in AV conduction.
  • An elevated relative PR variability index suggests inhomogeneous AV conduction in coronary atherosclerosis.