Related Experiment Video
Updated: Aug 29, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
[Orthostatic hypotension and its treatment in the elderly]
Jacques Boddaert1, Joël Belmin
1Centre de gériatrie, Pavillon Marguerite Bottard, Hôpital Pitié-Salpêtrière, Paris.
Abstract:
DEFINITION CRITERIA: Orthostatic hypotension (OH) is a frequent pathology in the elderly, defined, since the consensus meeting in 1996, as a drop in systolic blood pressure of > or = 20 mmHg and/or diastolic blood pressure of > or =10 mmHg, 1, 2 or 3 minutes after orthostatism. SEVERAL RISKS: Orthostatic hypotension is associated with the risk of falls and is a limiting factor in the patients' autonomy and quality of life. However, it is also an independent predictive factor of mortality, which should justify its fairly systematic research in the elderly. MULTIPLE CAUSES: Its multi-factor origin is enhanced by certain modifications related to age (autonomous nervous system, arterial wall), but above all by the numerous pathological situations and predominantly the iatrogenic disease, hypertension, or frequent situations in geriatrics such as anaemia and dehydration that must be systematically explored. THERAPEUTIC MEASURES: Its treatment relies on the elimination of the enhancing element, the patient's education, the wearing of elastic stockings and, at a later stage, administration of treatments such as midodrine.
Related Concept Videos
Drug Dosing: Geriatric Patients
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacodynamics in Geriatric Patients: Effects of Age
Hypertension IV: Drug Therapy and Lifestyle Modifications
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion