Related Experiment Video
Updated: Aug 29, 2026
Restraint to Induce Stress in Mice and Rats
Published on: December 6, 2024
Effect of stress on variability of systemic hemodynamics in rats of various genetic strains
L M Belkina1, O S Tarasova, T N Kirillina
1Institute of General Pathology and Pathomorphology, Russian Academy of Medical Sciences, Moscow. lmgb@yandex.ru
Abstract:
Power spectral density of heart rate fluctuations in the range of 0.02-5.00 Hz in August rats was lower than in Wistar rats. Changes in mean blood pressure and heart rate during stress (15-min immobilization) were similar in animals of both strains. As differentiated from Wistar rats, power spectral density of fluctuations in August rats considerably decreased after stress. August rats were characterized by low spectral power at rest and high resistance to the arrhythmogenic effect of 10-min acute myocardial ischemia.
