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Childhood constipation is not associated with characteristic fingerprint patterns
C R Jackson1, B Anderson, B Jaffray
1University of Newcastle upon Tyne, UK.
Insights
Simple arch fingerprint patterns are not linked to severe childhood constipation or its genetic causes. This study found no association, suggesting fingerprint patterns do not help predict or manage this condition.
Area of Science:
- Pediatric Gastroenterology
- Dermatoglyphics
- Genetics
Background:
- A potential association between simple arch fingerprint patterns and severe childhood constipation has been proposed.
- Such an association could offer predictive value for disease prognosis.
Purpose of the Study:
- To investigate the prevalence of simple arch fingerprint patterns in children with severe constipation compared to controls.
- To examine the occurrence of these patterns in first-degree relatives of both groups.
Main Methods:
- Fingerprint patterns were analyzed by blinded assessors in 30 surgically treated constipated children and 30 appendicitis controls.
- First-degree relatives of participants were also included.
- Colonic transit times and clinical outcomes were assessed in constipated children.
Main Results:
- Similar proportions of constipated children (13%) and controls (7%) exhibited simple arches.
- Arch positivity was more frequent in relatives of arch-positive children (6/6) than arch-negative children (14/54).
- Fingerprint patterns did not correlate with prolonged colonic transit times or the need for colectomy.
Conclusions:
- Simple arch fingerprint patterns are not associated with severe childhood constipation.
- These patterns do not aid in the management or prediction of severe constipation.
- The findings do not support a genetic basis for severe constipation linked to fingerprint patterns.
Background:
It has been suggested that there is an association between simple arch fingerprint patterns and severe childhood constipation. If real, this association might be useful to predict which children have a poor prognosis.
Aim:
To see how many severely constipated children have simple arches, compared to non-constipated controls and their first degree relatives.
Methods:
Fingerprints were classified by two blinded assessors in 30 children requiring surgery for refractory constipation, and 30 children with appendicitis, and the first degree relatives of both groups. Colonic transit times and clinical outcomes were also evaluated among constipated children.
Results:
At least one simple arch was found in similar numbers of constipated children (13%) and their families (16%), and control children (7%) and their families (13%). Arch positivity was commoner among relatives of arch positive (6/6) than arch negative children (14/54), regardless of bowel history. Arch positivity did not identify children with prolonged transit times, nor those who required colectomy.
Conclusions:
Fingerprint patterns are not associated with severe childhood constipation, do not aid their management, and do not support a genetic aetiology for this problem.
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