Related Experiment Video
Updated: Aug 29, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
[Natural evolution of coronary artery ectasia after coronary artery bypass grafting]
H Ohno1, M Higashidate, T Yokosuka
1Department of Cardiovascular Surgery, National Yokohama Medical Center, Yokohama, Japan.
Insights
Coronary artery aneurysms, a variant of coronary artery disease, can progress despite bypass surgery. Surgical ligation and grafting successfully treated a large right coronary artery aneurysm with significant stenosis.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Medicine
Background:
- Coronary artery aneurysm and ectasia are uncommon manifestations of atherosclerotic coronary artery disease.
- Atherosclerotic coronary artery disease (CAD) can lead to complex vascular changes, including aneurysms.
Observation:
- A 49-year-old male presented with progression of right coronary artery ectasia to a large aneurysm.
- The patient had undergone initial coronary artery bypass grafting 6 years prior and had advanced obstructive CAD.
- Fragile fresh clot formation was noted within the aneurysm, despite standard coumadin therapy.
Findings:
- Surgical management involved ligation of the aneurysm and distal bypass grafting under cardiopulmonary bypass.
- The case highlights the challenges in managing large coronary artery aneurysms associated with significant coronary stenosis.
Implications:
- This case underscores the importance of considering surgical intervention for complex coronary artery aneurysms.
- Effective management strategies are crucial for patients with dilated coronary arteries and concurrent stenosis.
- Further discussion on surgical techniques for these rare but serious conditions is warranted.
Abstract:
Coronary artery aneurysm and ectasia, unusual angiographic findings, are considered as variant of atherosclerotic coronary artery disease. A 49-year-old man whose right coronary artery ectasia had progressed to large aneurysm, accompanied by advanced obstructive coronary artery disease, 6 years after the initial coronary artery bypass grafting. It was treated with ligation of aneurysm and distal bypass grafting under cardiopulmonary bypass. Fragile fresh clot was formed within the aneurysm irrespective of coumadin therapy as a standard regimen for the coronary artery ectasias. We will discuss the surgical management for the dilated coronary artery with significant coronary stenosis.
More Related Videos
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
Published on: April 24, 2017
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018