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[Definition of chronic obstructive disease].

Takateru Izumi1

  • 1Kyoto University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 17, 2003
PubMed
Summary

Chronic obstructive pulmonary disease (COPD) is an obstructive ventilatory disorder. While historically linked to smoking, its definition as a distinct disease state with irreversible airflow limitation remains challenging.

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Area of Science:

  • Pulmonology
  • Respiratory Medicine

Context:

  • Chronic obstructive pulmonary disease (COPD) was initially defined as a combination of chronic bronchitis and pulmonary emphysema.
  • Historically, COPD has been predominantly associated with smoking as its primary cause.
  • The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline in 2001 proposed a revised definition focusing on airflow limitation.

Purpose:

  • To explore the historical definitions and evolution of Chronic Obstructive Pulmonary Disease (COPD).
  • To highlight the diagnostic challenges and ongoing debate surrounding the precise definition of COPD.
  • To differentiate between the older concept of COPD as a combination of diseases and the current understanding of airflow limitation.

Summary:

  • COPD was first described as a condition encompassing chronic bronchitis and pulmonary emphysema, presenting with chronic dyspnea.
  • The understanding of COPD evolved, with the 2001 GOLD guidelines defining it as a disease state characterized by not fully reversible airflow limitation.
  • Despite revised definitions, challenges persist in definitively characterizing COPD as a distinct disease entity.

Impact:

  • Clarifies the historical and current understanding of COPD definitions.
  • Emphasizes the persistent challenges in COPD diagnosis and classification.
  • Provides a foundation for further research into the precise etiological and pathological characteristics of COPD.

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