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T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens
A Jeurissen1, J L Ceuppens, X Bossuyt
1Experimental Laboratory Medicine, Department of Molecular Cell Biology, Faculty of Medicine, Catholic University Leuven, Leuven, Belgium.
Immunology
|December 18, 2003
Abstract
No abstract available in PubMed .
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Cell-mediated Immune Responses
Overview
T Cell Types and Functions
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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